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summary
Radiological protection. Performance criteria for laboratories using the cytokinesis-block micronucleus (CBMN) assay in peripheral blood lymphocytes for biological dosimetry. | Status: Superseded, Withdrawn
description
1 Scope
This International Standard addresses the following:
- a) confidentiality of personal information for the customer and the laboratory;
- b) laboratory safety requirements;
- c) radiation sources, dose rates, and ranges used for establishing the calibration reference dose-effect curves allowing the dose estimation from CBMN assay yields and the minimum resolvable dose;
- d) performance of blood collection, culturing, harvesting, and sample preparation for CBMN assay scoring;
- e) scoring criteria;
- f) conversion of micronucleus frequency in binucleated cells into an estimate of absorbed dose;
- g) reporting of results;
- h) quality assurance and quality control;
- i) informative annexes containing examples of a questionnaire, instructions for customers, a microscope scoring data sheet, a sample report and advice on strengths and limitations of current automated systems for automated micronucleus scoring.
Details
Publisher
BS
File size
963.14 KB
Pages
40
Format
PDF
Publication date
2018-01-31
ISBN-13
978-0-580-96932-4
ISBN-13 plain
9780580969324
ISBN-10
0580969324
