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Radiological protection. Performance criteria for laboratories using the cytokinesis-block micronucleus (CBMN) assay in peripheral blood lymphocytes for biological dosimetry. | Status: Current
description
1 Scope
This document gives guidance on
- a) confidentiality of personal information for the customer and the laboratory,
- b) laboratory safety requirements,
- c) calibration sources and calibration dose ranges useful for establishing the reference dose-response curves that contribute to the dose estimation from CBMN assay yields and the detection limit,
- d) performance of blood collection, culturing, harvesting, and sample preparation for CBMN assay scoring,
- e) scoring criteria,
- f) conversion of micronucleus frequency in BNCs into an estimate of absorbed dose,
- g) reporting of results,
- h) quality assurance and quality control, and
- i) informative annexes containing sample instructions for customers, sample questionnaire, a microscope scoring data sheet, and a sample report.
Details
Publisher
BS
File size
1.18 MB
Pages
46
Format
PDF
Publication date
2024-06-28
ISBN-13
978-0-539-19945-1
ISBN-13 plain
9780539199451
ISBN-10
0539199451
