What is ISO 21363 about?
ISO 21363 discusses measurements of particle size and shape distributions by transmission electron microscopy for nanotechnologies. ISO 21363 outlines how to capture, measure and analyse transmission electron microscopy images to obtain particle size and shape distributions in the nanoscale.
ISO 21363 broadly is applicable to nano-objects as well as to particles with sizes larger than 100 nm. The exact working range of the method depends on the required uncertainty and on the performance of the transmission electron microscope. These elements can be evaluated according to the requirements described in this document.
Who is ISO 21363 for?
ISO 21363 on particle size and shape distributions by transmission electron microscopy is useful for:
- Manufacturers of nanotechnologies
- Test centers for nanotechnologies
- Regulatory authorities
Why should you use ISO 21363?
Characterization procedures for nanoparticles often include but are not limited to, size, shape, surface structure (or texture), and surface chemistry. These measurements, combined with phase information, such as crystalline phase, constitute the morphology of the material.
ISO 21363 focuses on two attributes of morphology, size, and shape distributions, for discrete, agglomerated, and aggregated nanoobjects (materials with at least one dimension in the nanoscale, 1 nm < a length dimension < 100 nm).
ISO 21363 guidelines helps you with requirements on TEM measurements procedures, sample preparations, instrumental factors, image capture, particle analysis, data analysis, and reporting for measurements of particle size and shape distributions by transmission electron microscopy for nanotechnologies. This helps in improving qualitative and quantitative quality metrics plus visualization and correlation tools. ISO 21363 permits users to tailor the protocol to their qualitative and quantitative quality targets.
