BS ISO 21439:2009 Clinical dosimetry. Beta radiation sources for brachytherapy
BS ISO 21439 specifies methods for the determination of absorbed-dose distributions in water or tissue that are required prior to initiating procedures for the application of beta radiation in ophthalmic tumour and intravascular brachytherapy.
BS ISO 21439 gives recommendations for beta radiation source calibration, dosimetry measurements, dose calculation, dosimetric quality assurance, as well as for beta radiation brachytherapy treatment planning. BS ISO 21439 also gives guidance for estimating the uncertainty of the absorbed dose to water.
BS ISO 21439 applies to “sealed” radioactive sources, such as plane and concave surface sources, source trains of single seeds, line sources, and shell and volume sources, for which only the beta radiation emitted is of therapeutic relevance.
BS ISO 21439 is geared towards organizations wishing to establish reference methods in dosimetry aiming at clinical demands for an appropriately small uncertainty of the delivered dose. BS ISO 21439 does not exclude the possibility that there can be other methods leading to the same or smaller measurement uncertainties.
Contents of BS ISO 21439:
• Foreword
• Introduction
• Scope
• Normative references
• Terms and definitions
• Beta radiation sources and source data
• Dose calculation parameters and formalisms
• Calibration and traceability
• Dose measurements in-phantom and measurement corrections
• Theoretical modelling
• Uncertainties in source calibrations
• Treatment planning and reporting
• Clinical quality control
• Reference data
• Reference data sheet examples
• Primary standards for beta radiation dosimetry
• Detectors and phantom materials for clinical dosimetry of beta radiation
• brachytherapy sources
• Monte Carlo calculations
• Treatment planning
• Bibliography
