What is ISO 23904 about?
ISO 23904 is a standard that covers HPLC-FLD method for cigarette mainstream smoke with an intense smoking regime which enables accurate determination of phenolic compounds in cigarettes and regulate their content.
ISO 23904 specifies a method for the quantification of selected phenolic compounds by high performance liquid chromatography with fluorescence detection (HPLC-FLD) using ISO 20778 smoking parameters. The selected phenolic compounds are: hydroquinone, resorcinol, catechol, phenol, p-Cresol, m-Cresol and o-Cresol.
ISO 23904 method is applicable to cigarettes with total particulate matter (TPM) yields between 20 mg/cigarette and 45 mg/cigarette.
Who is ISO 23904 for?
ISO 23904 on phenolic compounds in cigarettes applies to:
- Manufacturers of cigarettes
- Distributors and importers of cigarettes
- Testing houses and labs for cigarettes
- Government regulators
Why should you use ISO 23904?
Often, smoking cigarettes is the main source of exposure to phenolic compounds in humans. Many of these phenolic compounds fall under the category of possible human carcinogens. They are found to promote tumours, damage DNA and cause irritation in the eyes, nose and throat.
ISO 23904 provides you guidance on high-performance liquid chromatography with a fluorescence detection method that uses a glass fibre filter pad as trapping mechanism to accurately determine phenolic compounds in cigarettes.
ISO 23904 method is based on results obtained in a collaborative study that involved 18 laboratories using cigarettes manufactured from a range of blend styles that ensures the authenticity and accuracy of the method.
ISO 23904 ensures that you perform the method accurately by providing you with a step-by-step procedure for the method.
The guidance in ISO 23904 enables you to identify phenolic content in cigarettes to regulate its content and limit toxic exposure caused by smoke.
