What is ISO/TS 23459 about?
ISO/TS 23459 addresses nanotechnologies that specify measurement protocols and test conditions to determine alterations to protein secondary structure induced by their interaction with nanomaterials using ultraviolet circular dichroism (UV-CD) spectroscopy.
ISO/TS 23459 does not apply to the characterization of conformational changes of disordered proteins.
Who is ISO/TS 23459 for?
ISO/TS 23459 on nanotechnology is useful for-
- Nanotechnology laboratories
- Pharmaceutical and biomedical laboratories
- Research facilities
Why should you use ISO/TS 23459?
Nano-objects and their aggregates and agglomerates (NOAA) are currently produced in large mass quantities globally and used in a variety of applications. However, there is concern about their interaction with biological systems, including proteins, which could lead to reversible or irreversible alterations in their secondary structure.
ISO/TS 23459 guidelines provide information on test methods such as high-field nuclear magnetic resonance (NMR), Fourier-transform infrared (FT-IR), Raman spectroscopy, and ultraviolet circular dichroism (UV-CD) spectroscopies which help you in proper assessments of protein secondary structure during an interaction with nanomaterials using ultraviolet circular dichroism and will give reliable results and will be reproducible in any laboratory.
